Known since the eighteenth century as Villa Piperatorum, he was part of the county of Mede, derived from the ancient county of Lomello. The Biscossi or Biscossa, who were part of the large estate of the Counts of Mede, were its owners. The history of the Palace and the feud rooted in the thirteenth century, when the territory of Villa Biscossi was known as Villa Piperis or Piperatorum. It was a small town that was named, as usual, the largest owner family formerly living in these places, the Biscossi, who settled in the area in the late thirteenth century. Casale palace, built in the square in front of the sixteenth-century church, dominates the town, with its elegant portico with granite columns and the terrace. The large windows of the first floor seem to refer to buildings bunting architect GA Veneroni, active in Pavia in the eighteenth century, which could be named the construction of the entire building. Behind the palace a large garden contains many species of plants and a small lake, connected to the irrigation canals of the ancient farm. The ownership of the Palace passed to Pallestrini Provera, who received Vittorio Emanuele II and Cavour, and then sent to Casale. While the small town of Villa Biscossi remained alive and vital with its agricultural activities and crafts linked, the Palace underwent a period of decadence to the '30s, due to the absence of the owners. Today the Palazzo Casale, after being restored, is open to the public and made available for weddings and private events.